Renal clearance is a significant route of elimination of water-soluble drugs and drug metabolites. It is a measure of the ability of the kidneys to eliminate drugs and is the net result of glomerular filtration, tubular secretion, and tubular resorption.
This calculator calculates the renal clearance using filtration rate, rate of secretion, rate of reabsorption values.
Formula:
Where,
CP is the plasma drug concentration