The Khorana Score Calculator is an essential tool for oncologists to predict the risk of chemotherapy-associated venous thromboembolism (VTE) in cancer patients. Understand and manage the risk of DVT and PE effectively to improve patient outcomes and guide prophylactic interventions.
Formula:
The Khorana Score is calculated by summing points from specific risk factors:
- Site of Cancer: Very High Risk (stomach, pancreas) = 2 points; High Risk (lung, lymphoma, gynecologic, bladder, testicular, renal, multiple myeloma) = 1 point; Low Risk (all others) = 0 points
- Pre-chemotherapy Platelet Count: ≥ 350 x 109/L = 1 point; < 350 x 109/L = 0 points
- Hemoglobin Level: < 100 g/L OR use of erythropoiesis-stimulating agents (ESA) = 1 point; ≥ 100 g/L AND no ESA use = 0 points
- White Blood Cell (WBC) Count: > 11 x 109/L = 1 point; ≤ 11 x 109/L = 0 points
- Body Mass Index (BMI): ≥ 35 kg/m2 = 1 point; < 35 kg/m2 = 0 points