Hemodialysis PCR Calculator: Estimate Protein Catabolic Rate (nPCR) & Kt/V

Calculate Hemodialysis Protein Catabolic Rate (nPCR) & Kt/V

mg/dL
mg/dL
hours
kg
mL/min
Enter 0 if the patient has no residual renal function.

Utilize our comprehensive Hemodialysis PCR Calculator to accurately determine the Protein Catabolic Rate (nPCR) and Kt/V for hemodialysis patients. This vital tool helps assess dialysis adequacy and nutritional status by leveraging pre/post-dialysis BUN levels, session duration, patient weight, and residual renal function. Improve patient care with precise calculations and support optimal nutritional management for patients with End-Stage Renal Disease (ESRD).

Formula:

To estimate the Normalized Protein Catabolic Rate (nPCR) and Kt/V, the following formulas are used:

1. Kt/V (Daugirdas 2nd Generation Formula):

Kt/V = -ln(R - 0.008 × t) + (4 - 3.5 × R) × 0.03 × t

Where:
  • R = Post-dialysis BUN / Pre-dialysis BUN
  • t = Dialysis Session Duration (hours)
  • ln = Natural logarithm

2. Normalized Protein Catabolic Rate (nPCR):

nPCR (g/kg/day) = (0.025 × Kt/V) + 0.091 + (0.043 × Residual Urea Clearance)

Where:
  • Kt/V = Calculated Kt/V value
  • Residual Urea Clearance = Patient's residual renal function (mL/min)

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